INGREDIENTS PEPTIDES/PROTEINS    주소복사

PEPTIDES/PROTEINS

 

 

LayN-Elastin 

 


  -. Elatin is a major extracellular matrix proteins with collagen

 

  -. Elastin is highly elastic protein in connective tissues and allows many tissues in the body including skin to

     resume their shape

 

  -. The lysine residues of cross-linking domain are deaminated by lysyl oxidase and conform stable elastin

     polymer

  

 Functions

  ● Major extracellular matrix (ECM) protein in tissues

  ● Formation of elastin fibers in skin dermis and repair or fill worn out elastin fibers

  ● LayN-Elastin will be delivered to skin dermis. Elastin fibers are present in dermis

 

 

 

LayN-SOD

 

  -. LayN-SOD is a recombinant protein combining LayN-Pep and Human SOD1 (Superoxide Dismutase 1)

 

  -. SOD is an enzymatic anti-oxidant protein naturally present in the human body

 

  -. Protecting the skin from external stresses and photo-aging

 

  -. LayN-Pep effectively deliver SOD protein to inner skin layers

 

 Functions

  ● Anti-Oxidant

     Neutralizing the superoxide free radicals

     (Source: Dermatoendocrinol. 2012 1;4(3):232-235)

  ● Skin Protection during RT (Radiation Therapy)

     Scavenger for ROS and free radicals

     (Source: Drug Discov. Ther. 2012;6(4):169-177)

  ● Anti-Inflammation

     Inhibition of UV-induced skin inflammation

     (Source: Exp. Dermatol. 1997;6(3):116-121)

  ● Inhibition of Skin Fibrosis

     Exchange myofibroblasts into fibroblasts

     (Source: Free Radic. Biol. Med. 2001 1;30(1):30-42)

 


 

LayN-BROM

 

  -. LayN-BROM is a recombinant protein combining LayN-Pep and Bromelain (Ananas comosus

     (Pineapple), Stem)

 

  -. Bromelain is a main peptidase in pineapple stem extracts

 

  -. Pineapple extracts containing bromelain have a long traditional medicine among the natives of south

     and central america for wound healing, burn and anti-swelling/bruising

 

 Functions

  ● Anti-Inflammation

     (Source: Evid. Based Complement Alternat. Med. 2004;1(3):251-257)

  ● Anti-Swelling/Bruising

     (Source: J. Obstet. Gynaecol. Br. Commonw. 1972;79(10):951-953)

  ● Anti-Tumor

     (Sources: Cancer Lett. 2010 28;290(2):148-156, Planta Med. 2007;73(13):1377-1383)

  ● Wound Healing

     (Source: J. Surg. Res. 2012;176(2):503-509)

 

 

 

LayN-TB4X

 

  -. LayN-TB4X is a recombinant protein combining LayN-Pep and Human TB4X (Thymosin beta-4)

 

  -. TB4X is a actin sequestering protein which plays a role in regulation of actin polymerization in almost

     human cells

 

  -. TB4X is involved in cell proliferation, differentiation and migration

 

 Functions

  ● Wound Healing

     Angiogenesis by endothelial cell differentiation & migration

     Stimulate collagen synthesis & deposition

     (Source: J. Invest. Dermatol. 1999;113(3):364-368)

  ● Hair Growth

     Hair follicles stem cell growth, differentiation & migration

     (Sources: Ann. N Y Acad. Sci. 2007;1112:95-103, FASEB J. 2004;18(2):385-387)

 

 

 

LayN-TRX

 

  -. LayN-TRX is a recombinant protein combining LayN-Pep and Human TRX (Thioredoxin)

 

  -. TRX is a small protein that act as a antioxidant ubiquitously present in human body

 

  -. TRX is modulate cellular red-ox signals and maintain cellular oxidation state

 

 Functions

  ● Anti-Oxidant

     Maintain cellular oxidation state by transduction of red-ox signals

     (Source: Proc. Natl. Acad. Sci. 1999 30;96(7):4131-4136)

  ● Anti-Inflammation

     (Source: Ann. N Y Acad. Sci. 2005;1055:1-12)